Methyl 3-(3-hydroxypropyl)benzoate → Methyl 3-(3-oxopropyl)benzoate

HRID 231099Notes

Reaction equation

HRID 231099 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([CH2:11][CH2:12][CH2:13][OH:14])[CH:8]=[CH:9][CH:10]=1)=[O:4]>N1C=CC=CC=1.[O-2].[O-2].[O-2].[Cr+6]>[CH3:1][O:2][C:3]([C:5]1[CH:6]=[C:7]([CH2:11][CH2:12][CH:13]=[O:14])[CH:8]=[CH:9][CH:10]=1)=[O:4]

Participants

4

Reactant 1

HCID 15282060Methyl 3-(3-hydroxypropyl)benzoate

Product 1

HCID 10352555Methyl 3-(3-oxopropyl)benzoate

Reagents, catalysts & solvents 2

HCID 10219390chromium (VI) trioxideCatalystHCID 1049PyridineSolvent

Procedure

3-(3-Methoxycarbonylphenyl)propanol (1.9 g) was oxidised with chromium trioxide (5.0 g) in pyridine (7.9 ml) as described in Example 1(e) to give the product as a pale oil.

Sources & evidence

ORD record
ord-49afc5a58e9a490f8ca2744f1c30ba39
Source dataset
uspto-grants-1989_07
Patent number
US04845110

Reaction notes

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