3-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridine → 1-(tert-butoxycarbonyl)-4-[N-(2-methoxyphenyl)-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine

HRID 2311107Notes

Reaction equation

HRID 2311107 reaction equation
[CH3:1][O:2][c:3]1[c:4]([NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:5][cH:6][cH:7][cH:8]1.[Cl:23][CH2:24][c:25]1[cH:26][c:27](-[c:31]2[cH:32][c:33]([O:41][CH3:42])[c:34]([O:39][CH3:40])[c:35]([O:37][CH3:38])[cH:36]2)[cH:28][n:29][cH:30]1>>[CH3:1][O:2][c:3]1[c:4]([N:9]([CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[CH2:24][c:25]2[cH:26][c:27](-[c:31]3[cH:32][c:33]([O:41][CH3:42])[c:34]([O:39][CH3:40])[c:35]([O:37][CH3:38])[cH:36]3)[cH:28][n:29][cH:30]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

3

Reactant 2

HCID 225578743-Chloromethyl-5-(3,4,5-trimethoxyphenyl)pyridineHCID 22557919tert-Butyl 4-((2-methoxyphenyl)amino)piperidine-1-carboxylate

Product 1

HCID 225579121-(tert-butoxycarbonyl)-4-[N-(2-methoxyphenyl)-N-[[3-(3,4,5-trimethoxyphenyl) pyridin-5-yl]methyl]amino]piperidine

Sources & evidence

ORD record
ord-f43fb1f2821945f4a1a2a5f393db0ad9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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