Oxalic Acid → HCID 20034510, compound

Participants

Reaction Steps

3.6 g of 4-{2-[4-(2-ethoxyethyl)-2-methylphenoxy]ethylamino}thieno[2,3-d]pyrimidine were dissolved in 30 ml of acetone, and 0.9 g of anhydrous oxalic acid dissolved in 30 ml of acetone was added thereto. Reaction occurred at once, and crystals separated. The mixture was stirred for a further 30 minutes whilst heating. The mixture was cooled, and the crystals were collected by filtration and recrystallized from acetone to give 3.9 g of the title compound as colorless columnar crystals melting at 151°-152° C.

Provenance & Evidence