Methanol → 3-(5-Fluoro-4-hydroxy-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline
Reaction equation
[BH4-:1].[CH3:3][OH:4].[F:5][c:6]1[c:7]2[c:12]([cH:13][cH:14][cH:15]1)[C:11]([c:16]1[cH:17][n:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[cH:25]1)=[N:10][C:9]([CH3:26])([CH3:27])[C:8]2=[O:28].[Na+:2].[OH2:29]>>[F:5][c:6]1[c:7]2[c:12]([cH:13][cH:14][cH:15]1)[C:11]([c:16]1[cH:17][n:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[cH:25]1)=[N:10][C:9]([CH3:26])([CH3:27])[CH:8]2[OH:28]Participants
6
Sources & evidence
- ORD record
- ord-d55a6107918d4a82b5108f9f5edc7330
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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