Lauric Acid → Propyl laurate

HRID 231146Notes

Reaction equation

HRID 231146 reaction equation
O[C:2]1[C:11]2C(=C(C(F)(F)F)C=CC=2)N=C(C(O)CC)[C:3]=1C(NC1SC=CN=1)=O.[C:28]([OH:41])(=[O:40])[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39]>>[C:28]([O:41][CH2:3][CH2:2][CH3:11])(=[O:40])[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH3:39]

Participants

3

Reactant 2

HCID 3893Lauric AcidHCID 178458925HCID 178458925, compound

Product 1

HCID 77255Propyl laurate

Procedure

Using the procedure of Example 15, 5 g of 4-hydroxy-2-(1-hydroxypropyl)-N-(2-thiazolyl)-8-trifluoromethyl-3-quinoline carboxamide and 2.8 g of lauric acid were reacted to obtain 6 g of 1-(4-hydroxy-3-(2-thiazolylamino)-carbonyl]-8-(trifluoromethyl)-2-quinolinyl]-propyl dodecanoate melting at 158° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-3f84151eeba64e0a910bf63e57b88265
Source dataset
uspto-grants-1989_07
Patent number
US04845105

Reaction notes

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