Carbonate Ion → 4-[(9-cyclopentyl-5-methyl-6-oxospiro[8H-pyrimido[4,5-b][1,4]diazepine-7,1'-cyclopropane]-2-yl)amino]-2,5-difluoro-N-(1-methylpyrrolidin-3-yl)benzamide
Reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:13]([n:14]1)[N:12]([CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19]1)[CH2:11][C:8]1([C:7](=[O:20])[N:6]2[CH3:21])[CH2:9][CH2:10]1.[Cs+:44].[Cs+:45].[NH2:22][c:23]1[cH:24][c:25]([F:39])[c:26]([C:27](=[O:28])[NH:29][CH:30]2[CH2:31][N:32]([CH3:35])[CH2:33][CH2:34]2)[cH:36][c:37]1[F:38].[O:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1>>[c:2]1([NH:22][c:23]2[cH:24][c:25]([F:39])[c:26]([C:27](=[O:28])[NH:29][CH:30]3[CH2:31][N:32]([CH3:35])[CH2:33][CH2:34]3)[cH:36][c:37]2[F:38])[n:3][cH:4][c:5]2[c:13]([n:14]1)[N:12]([CH:15]1[CH2:16][CH2:17][CH2:18][CH2:19]1)[CH2:11][C:8]1([C:7](=[O:20])[N:6]2[CH3:21])[CH2:9][CH2:10]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a02eaf9ca9214c0383c8dbfa006cfb81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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