m-Chloroperbenzoic acid → HCID 20034625, compound

Participants

Reaction Steps

850 mg (2 mmol) of the title compound from Example 21 were dissolved in 50 ml of CH2Cl2, and 50 ml of aqueous Na2HPO4 /KH2PO4 buffer solution (pH 7.5; 7.4 ml of KH2PO4 solution (45.35 g/l)+42.5 ml of Na2HPO4 solution (59.5 g/l) were added. While stirring vigorously at room temperature, 500 mg (2.5 mmol) of m-chloroperbenzoic acid dissolved in CH2Cl2 were added dropwise. The organic phase was dried over MgSO4 and concentrated, and the residue was chromatographed on silica gel using ethyl acetate. The title compound crystallized from isopropanol. Melting point 119°-120° C.

Provenance & Evidence