2-(6-Bromopyridin-2-yl)-2-morpholin-4-ylethanol → 2-{[6-(2-Hydroxy-1-morpholin-4-ylethyl)pyridine-2-yl]amino}-5-(6-piperidin-1-ylpyridin-3-yl)thiophene-3-carboxamide
Reaction equation
[Br:22][c:23]1[cH:24][cH:25][cH:26][c:27]([CH:29]([CH2:30][OH:31])[N:32]2[CH2:33][CH2:34][O:35][CH2:36][CH2:37]2)[n:28]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][n:12][c:13]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]3)[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[cH:11][n:12][c:13]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]3)[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:23]1[cH:24][cH:25][cH:26][c:27]([CH:29]([CH2:30][OH:31])[N:32]2[CH2:33][CH2:34][O:35][CH2:36][CH2:37]2)[n:28]1Participants
3
Sources & evidence
- ORD record
- ord-f8a88d60e745487aa0637a1c4ac9b58d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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