1-(4-(2-(Dimethylcarbamoyl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-3-(2-phenylacetyl)thiourea → N-(3-Fluoro-4-(6-(pyrrolidine-1-carbonyl)thieno[2,3-d]pyrimidin-4-yloxy)phenylcarbamothioyl)-2-phenylacetamide
Reaction equation
[CH3:26][N:27]([CH3:28])[C:29]([c:30]1[s:31][c:32]2[c:33]([n:34][cH:35][cH:36][c:37]2[O:38][c:39]2[cH:40][cH:41][c:42]([NH:43][C:47](=[S:48])[NH:49][C:50]([CH2:51][c:52]3[cH:53][cH:54][cH:55][cH:56][cH:57]3)=[O:58])[cH:44][c:45]2[F:46])[cH:59]1)=[O:60].[NH2:1][c:2]1[cH:3][c:4]([F:25])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][n:12]2)[s:13][c:14]([C:16](=[O:17])[N:18]2[CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:15]3)[cH:23][cH:24]1>>[NH:1]([c:2]1[cH:3][c:4]([F:25])[c:5]([O:6][c:7]2[c:8]3[c:9]([n:10][cH:11][n:12]2)[s:13][c:14]([C:16](=[O:17])[N:18]2[CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:15]3)[cH:23][cH:24]1)[C:47](=[S:48])[NH:49][C:50]([CH2:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1)=[O:58]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ceb8d021ddce427eb7df8cbc87f38e9c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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