Methanol → {4-[(3-Chloro-2-fluorophenyl)amino]-7-methoxyquinazolin-6-yl}methanol
Reaction equation
[BH4-:1].[CH3:26][OH:27].[Cl:3][c:4]1[c:5]([F:25])[c:6]([NH:10][c:11]2[n:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:23][CH3:24])[c:18]([CH:21]=[O:22])[cH:19][c:20]23)[cH:7][cH:8][cH:9]1.[Na+:2]>>[Cl:3][c:4]1[c:5]([F:25])[c:6]([NH:10][c:11]2[n:12][cH:13][n:14][c:15]3[cH:16][c:17]([O:23][CH3:24])[c:18]([CH2:21][OH:22])[cH:19][c:20]23)[cH:7][cH:8][cH:9]1Participants
5
Sources & evidence
- ORD record
- ord-d275600f5cc64681ac2853901ae4610f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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