5-bromo-N-(2-(dimethylamino)ethyl)thiophene-2-sulfonamide → 5-[7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiophene-2-sulfonic acid (2-dimethylamino-ethyl)-amide
Reaction equation
[CH3:25][N:26]([CH2:27][CH2:28][NH:29][S:30](=[O:31])(=[O:32])[c:33]1[s:34][c:35]([Br:38])[cH:36][cH:37]1)[CH3:39].[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[CH:13])[F:24]>>[F:1][CH:2]([c:3]1[cH:4][c:5](-[c:14]2[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]2)[n:6][c:7]2[n:8]1[n:9][cH:10][c:11]2[C:12]#[C:13][c:35]1[s:34][c:33]([S:30]([NH:29][CH2:28][CH2:27][N:26]([CH3:25])[CH3:39])(=[O:31])=[O:32])[cH:37][cH:36]1)[F:24]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-8cc969323bba47eabb86b319bc689ba0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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