1-{4-Hydroxy-5-[4-(trifluoromethyl)phenyl]thiophen-3-yl}ethan-1-one → 5-(2-cyanobutanoyl)-N-[1-[4-hydroxy-5-[4-(trifluoromethyl)phenyl]thiophen-3-yl]ethylideneamino]thiophene-2-carboxamide
Reaction equation
[C:20](#[N:21])[CH:22]([C:23](=[O:24])[c:25]1[cH:26][cH:27][c:28]([C:30](=[O:31])[NH:32][NH2:33])[s:29]1)[CH2:34][CH3:35].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[s:10][cH:11][c:12]([C:15](=[O:16])[CH3:17])[c:13]2[OH:14])[cH:7][cH:8]1)([F:18])[F:19]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[s:10][cH:11][c:12]([C:15]([CH3:17])=[N:33][NH:32][C:30]([c:28]3[cH:27][cH:26][c:25]([C:23]([CH:22]([C:20]#[N:21])[CH2:34][CH3:35])=[O:24])[s:29]3)=[O:31])[c:13]2[OH:14])[cH:7][cH:8]1)([F:18])[F:19]Participants
3
Sources & evidence
- ORD record
- ord-087f284454ba41eca3b6259b236b3813
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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