HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 14574967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 14574965 | HCID 14574965 | — |
| Catalyst | Borate(1-), tetrahydro-, bis(triphenylphosphine)copper(1+) | HCID 12406461 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 14574967 | HCID 14574967 | 70% |
Reaction Steps
By following the procedure employed in Preparation 1, E. and F., 3,3-(ethylenedioxy)glutaric acid mono benzyl ester prepared as described above in step A. (2.937 g, 10.48 mmole) was converted to the corresponding acid chloride with oxalyl chloride (3.0 ml, 34.39 mmole) in 30 ml of benzene. The acid chloride was reduced with bis(triphenylphosphine) copper (I) tetrahydroborate (6.32 g, 10.48 mmole) and triphenylphosphine (5.5 g, 20.97 mmole) in 50 ml of acetone. There was obtained 1.930 g, 70% yield of benzyl 3,3-(ethylenedioxy)-4-formylbutyrate, as a colorless syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04845229 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-0bbbe448de364fd29ce0efb68ca31384 |
| Source note | uspto-grants-1989_07 |