Dimethyl Sulfoxide → 6-[p-[4-(m-Chlorophenyl)-1-piperazinyl]phenyl]-1,2-dihydro-2-oxonicotinonitrile
Reaction equation
[CH3:30][S:31](=[O:32])[CH3:33].[Cl:17][c:18]1[cH:19][c:20]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[cH:21][cH:22][cH:23]1.[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[nH:9][c:10](=[O:16])[c:11]([C:12]#[N:13])[cH:14][cH:15]2)[cH:6][cH:7]1>>[c:2]1([N:27]2[CH2:26][CH2:25][N:24]([c:20]3[cH:19][c:18]([Cl:17])[cH:23][cH:22][cH:21]3)[CH2:29][CH2:28]2)[cH:3][cH:4][c:5](-[c:8]2[nH:9][c:10](=[O:16])[c:11]([C:12]#[N:13])[cH:14][cH:15]2)[cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-ce429a27d9674918981c2b4259988940
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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