Pyridine → 3-(7-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-3-yl)-1,1-dimethyl-2-propynyl pivalate

HRID 2312587Notes

Reaction equation

HRID 2312587 reaction equation
[C:24]([C:25]([CH3:26])([CH3:27])[CH3:28])(=[O:29])[Cl:30].[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:23])[N:9]([CH3:22])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1[C:16]#[C:17][C:18]([CH3:19])([CH3:20])[OH:21].[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:23])[N:9]([CH3:22])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1[C:16]#[C:17][C:18]([CH3:19])([CH3:20])[O:21][C:24]([C:25]([CH3:26])([CH3:27])[CH3:28])=[O:29]

Participants

4

Reactant 3

HCID 1049PyridineHCID 62493Pivaloyl chlorideHCID 198306547-chloro-4,5-dihydro-3-(3-hydroxy-3-methyl-1-butynyl)-5-methyl-6H-imidazo[1,5-a][1,4]benzodiazepin-6-one

Product 1

HCID 198306513-(7-chloro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepin-3-yl)-1,1-dimethyl-2-propynyl pivalate

Sources & evidence

ORD record
ord-560ab2faaf1a4ef6830cd047848912d5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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