Methyl iodide → 2-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyltrimethylammonium iodide

HRID 231264Notes

Reaction equation

HRID 231264 reaction equation
[CH3:1][O:2][CH:3]([CH2:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:4][S:5]([CH2:8][CH2:9][N:10]([CH3:12])[CH3:11])(=[O:7])=[O:6].[CH3:33][I:34]>CCOCC>[I-:34].[CH3:1][O:2][CH:3]([CH2:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH3:32])[CH2:4][S:5]([CH2:8][CH2:9][N+:10]([CH3:33])([CH3:12])[CH3:11])(=[O:6])=[O:7]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 144982652-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyldimethylamine

Product 1

HCID 144982482-[(2-Methoxy-3-octadecyloxypropyl)sulfonyl]ethyltrimethylammonium iodide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

In 5 ml of ether is dissolved 0.24 g of 2-[(2-methoxy-3-octadecyloxypropyl)sulfonyl]ethyldimethylamine to which is added 1 ml of methyl iodide. The solution is then stirred at room temperature for 2 days. The reaction liquid is concentrated under reduced pressure and the residue is treated with methanol to give 275 mg of the captioned compound as powder.

Workup

  1. customThe reaction liquid
  2. concentrationis concentrated under reduced pressure
  3. additionthe residue is treated with methanol

Sources & evidence

ORD record
ord-c41443b41d0f4024954fde2ad444d8d1
Source dataset
uspto-grants-1989_07
Patent number
US04845219

Reaction notes

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