反应详情

温度

60 °C

A mixture containing 26.5 g of 12-cyclohexyldodecanol, 27.4 g of epichlorohydrin, 52.6 g of a 50% aqueous sodium hydroxide solution, 2.0 g of cetyltrimethylammonium chloride and 300 ml of toluene is stirred at 60° C. for 24 hours. The resulting reaction mixture is then washed with water, dried and concentrated to leave a residue which in turn is purified by silica gel chromatography to obtain 22.8 g of the captioned compound as a colorless oily substance.

1. customThe resulting reaction mixture
2. washis then washed with water
3. customdried
4. concentrationconcentrated
5. customto leave a residue which in turn
6. customis purified by silica gel chromatography