Sodium Hydroxide → HCID 23695952, compound

Participants

Reaction Conditions

Reaction Steps

50 g (0.13 mol) of sodium dodecyl 2-hydroxy-3chloropropyl phosphate was charged into a reactor, to which 1000 ml of ethanol was added, followed by agitation and heating to 70° C. to give a uniform system. Thereafter, the reaction system was cooled down to room temperature, to which 62.5 g (0.13 mol) of a 0.0021 mol/g sodium hydroxide solution in ethanol was gradually added and agitated for 3 hours while keeping the temperature. The high performance liquid chromatography (hereinafter referred to as HPLC) analysis revealed that the peak for the starting material disappeared and a peak for a new product appeared. The precipitated NaCl was removed by filtration, followed by distillation of the ethanol under reduced pressure to obtain 46 g of sodium dodecyl glycidyl phosphate (yield 100%). 1H NMR (D2O, δ(ppm)): see FIG. 1

Provenance & Evidence