3-Chloro-4-fluoro-1-benzothiophene-2-carbonyl chloride → (4-{(3-Chloro-4-fluoro-benzo[b]thiophene-2-carbonyl)-[2-methoxy-5-(6-methyl-pyridin-3-yl)-benzyl]-amino}-cyclohexyl)-methyl-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH:9]1[CH2:10][CH2:11][CH:12]([NH:15][CH2:16][c:17]2[c:18]([O:30][CH3:31])[cH:19][cH:20][c:21](-[c:23]3[cH:24][n:25][c:26]([CH3:29])[cH:27][cH:28]3)[cH:22]2)[CH2:13][CH2:14]1)=[O:32].[Cl:33][c:34]1[c:35]2[c:36]([s:37][c:38]1[C:39](=[O:40])[Cl:41])[cH:42][cH:43][cH:44][c:45]2[F:46]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH:9]1[CH2:10][CH2:11][CH:12]([N:15]([CH2:16][c:17]2[c:18]([O:30][CH3:31])[cH:19][cH:20][c:21](-[c:23]3[cH:24][n:25][c:26]([CH3:29])[cH:27][cH:28]3)[cH:22]2)[C:39]([c:38]2[c:34]([Cl:33])[c:35]3[c:36]([s:37]2)[cH:42][cH:43][cH:44][c:45]3[F:46])=[O:40])[CH2:13][CH2:14]1)=[O:32]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-6b08f37b215346c7ba64283428fb80eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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