Tert-butyl 4-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-iodopyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate → tert-Butyl 4-(7-(bis((2-(trimethylsilyl)ethoxy)methyl)amino)-3-(quinolin-3-yl)pyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate
Reaction equation
[CH3:1][Si:2]([CH2:3][CH2:4][O:5][CH2:6][N:7]([c:8]1[cH:9][c:10]([CH:27]2[CH2:28][CH2:29][CH:30]([CH2:33][C:34]([O:35][CH2:36][CH3:37])=[O:38])[CH2:31][CH2:32]2)[n:11][c:12]2[n:13]1[n:14][cH:15][c:16]2-[c:17]1[cH:18][n:19][c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]2[cH:26]1)[CH2:39][O:40][CH2:41][CH2:42][Si:43]([CH3:44])([CH3:45])[CH3:46])([CH3:47])[CH3:48].[CH3:49][Si:50]([CH3:51])([CH3:52])[CH2:53][CH2:54][O:55][CH2:56][N:57]([CH2:58][O:59][CH2:60][CH2:61][Si:62]([CH3:63])([CH3:64])[CH3:65])[c:66]1[n:67]2[n:68][cH:70][c:71]([I:79])[c:80]2[n:81][c:82]([CH:83]2[CH2:84][CH2:85][N:69]([C:72](=[O:73])[O:74][C:75]([CH3:76])([CH3:77])[CH3:78])[CH2:86][CH2:87]2)[cH:88]1.[CH3:89][Si:90]([CH3:91])([CH3:92])[CH2:93][CH2:94][O:95][CH2:96][N:97]([CH2:98][O:99][CH2:100][CH2:101][Si:102]([CH3:103])([CH3:104])[CH3:105])[c:106]1[n:107]2[n:108][cH:109][c:110]([I:111])[c:112]2[n:113][c:114]([CH:115]2[CH2:116][CH2:117][CH:118]([CH2:119][C:120]([O:121][CH2:122][CH3:123])=[O:124])[CH2:125][CH2:126]2)[cH:127]1>>[CH3:1][Si:2]([CH2:3][CH2:4][O:5][CH2:6][N:7]([c:8]1[cH:9][c:10]([CH:27]2[CH2:28][CH2:29][N:69]([C:72](=[O:73])[O:74][C:75]([CH3:76])([CH3:77])[CH3:78])[CH2:31][CH2:32]2)[n:11][c:12]2[n:13]1[n:14][cH:15][c:16]2-[c:17]1[cH:18][n:19][c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]2[cH:26]1)[CH2:39][O:40][CH2:41][CH2:42][Si:43]([CH3:44])([CH3:45])[CH3:46])([CH3:47])[CH3:48]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5107aca80a1a411fa91a2afc49e44f81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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