4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole → N-((2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-3-(dimethylaminosulfonyl)propan-1-amine

HRID 2313161Notes

Reaction equation

HRID 2313161 reaction equation
[CH3:1][N:2]([S:3](=[O:4])(=[O:5])[CH2:6][CH2:7][CH2:8][NH:9][CH2:10][c:11]1[cH:12][c:13]2[n:14][c:15]([Cl:26])[n:16][c:17]([N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[c:18]2[s:19]1)[CH3:27].[CH3:28][C:29]1([CH3:30])[C:31]([CH3:32])([CH3:33])[O:34][B:35]([c:36]2[c:37]3[cH:38][n:39][nH:40][c:41]3[cH:42][cH:43][cH:44]2)[O:45]1>>[CH3:1][N:2]([S:3](=[O:4])(=[O:5])[CH2:6][CH2:7][CH2:8][NH:9][CH2:10][c:11]1[cH:12][c:13]2[n:14][c:15](-[c:36]3[c:37]4[cH:38][n:39][nH:40][c:41]4[cH:42][cH:43][cH:44]3)[n:16][c:17]([N:20]3[CH2:21][CH2:22][O:23][CH2:24][CH2:25]3)[c:18]2[s:19]1)[CH3:27]

Participants

3

Reactant 2

HCID 454801864-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazoleHCID 866184503-[(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-amino]-propane-1-sulfonic acid dimethylamide

Product 1

HCID 59592934N-((2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-3-(dimethylaminosulfonyl)propan-1-amine

Sources & evidence

ORD record
ord-a1cfe64d251d483db1934dffce6af575
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…