3-(3,5-Difluoro-pyridin-2-yl)-4-fluorophenylboronic acid → 5-[3-(3,5-Difluoropyridin-2-yl)-4-fluorophenyl]-2-trifluoromethyl[1,8]-naphthyridine
Reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1.[F:16][c:17]1[c:18](-[c:26]2[n:27][cH:28][c:29]([F:33])[cH:30][c:31]2[F:32])[cH:19][c:20]([B:23]([OH:24])[OH:25])[cH:21][cH:22]1>>[c:2]1(-[c:20]2[cH:19][c:18](-[c:26]3[n:27][cH:28][c:29]([F:33])[cH:30][c:31]3[F:32])[c:17]([F:16])[cH:22][cH:21]2)[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-4b843651b7d543ed9f3e3c0d1f0c7ff3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…