2-(7-amino-1,2,4,5-tetrahydro-benzo[d]azepin-3-yl)-N-methyl-acetamide → 2-[5-Chloro-2-(3-methylcarbamoylmethyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylamino)-pyrimidin-4-ylamino]-N-ethyl-3-fluoro-benzamide
Reaction equation
[Cl:18][c:19]1[n:20][cH:21][c:22]([Cl:38])[c:23]([NH:25][c:26]2[c:27]([C:28](=[O:29])[NH:30][CH2:31][CH3:32])[cH:33][cH:34][cH:35][c:36]2[F:37])[n:24]1.[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:16][cH:17]1)[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH:14][CH3:15])[CH2:9][CH2:10]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:5]([cH:16][cH:17]1)[CH2:6][CH2:7][N:8]([CH2:11][C:12](=[O:13])[NH:14][CH3:15])[CH2:9][CH2:10]2)[c:19]1[n:20][cH:21][c:22]([Cl:38])[c:23]([NH:25][c:26]2[c:27]([C:28](=[O:29])[NH:30][CH2:31][CH3:32])[cH:33][cH:34][cH:35][c:36]2[F:37])[n:24]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b48cd008a2bd41738432c9c0f1a9d7c4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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