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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2313720Generated: October 26, 2026

Tetrahydrofuran → methyl 5-[2-fluoro-4-[(2-fluorophenyl)methoxy]phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoate

https://huagongshe.com/reaction/2313720

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN,N,N',N'-TetramethylethylenediamineHCID 8037—
Reactant1-tert-Butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylateHCID 4175931—
Reactant4-Bromo-3-fluorophenyl (2-fluorophenyl)methyl etherHCID 59596706—
ReactantButyllithiumHCID 178418339—
Productmethyl 5-[2-fluoro-4-[(2-fluorophenyl)methoxy]phenyl]-2-[(2-methylpropan-2-yl)oxycarbonylamino]-5-oxopentanoateHCID 178500418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-61503ea7ead446e8a5eae3d24d5cce9d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)