HCID 11541444, compound → [2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-{5-[1-(2-hydroxy-ethyl)-1H-[1,2,3]triazol-4-yl]-2-methoxy-phenyl}-methanone

HRID 2313723Notes

Reaction equation

HRID 2313723 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[cH:7][cH:8][c:9]([F:10])[cH:11][c:12]2[F:13])[cH:14][cH:15][c:16]1[C:17]([c:18]1[cH:19][c:20](-[c:21]2[n:22][n:23][n:24]([CH2:25][CH2:26][O:27][CH:28]3[CH2:29][CH2:30][CH2:31][CH2:32][O:33]3)[cH:34]2)[cH:35][cH:36][c:37]1[CH3:38])=[O:39].[Cl:40][c:41]1[c:42]([C:56](=[O:57])[c:58]2[c:59]([O:78][CH3:79])[cH:60][cH:61][c:62](-[c:64]3[n:65][n:66][n:67]([CH2:69][CH2:70][O:71][CH:72]4[CH2:73][CH2:74][CH2:75][CH2:76][O:77]4)[cH:68]3)[cH:63]2)[cH:43][cH:44][c:45]([NH:47][c:48]2[c:49]([F:55])[cH:50][c:51]([F:54])[cH:52][cH:53]2)[cH:46]1>>[Cl:40][c:41]1[c:42]([C:56](=[O:57])[c:58]2[c:59]([O:78][CH3:79])[cH:60][cH:61][c:62](-[c:64]3[n:65][n:66][n:67]([CH2:69][CH2:70][OH:71])[cH:68]3)[cH:63]2)[cH:43][cH:44][c:45]([NH:47][c:48]2[c:49]([F:55])[cH:50][c:51]([F:54])[cH:52][cH:53]2)[cH:46]1

Participants

3

Reactant 2

HCID 11541444HCID 11541444, compoundHCID 11706669[2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-(2-methyl-5-{1-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-1H-[1,2,3]triazol-4-yl}-phenyl)-methanone

Product 1

HCID 11554848[2-Chloro-4-(2,4-difluoro-phenylamino)-phenyl]-{5-[1-(2-hydroxy-ethyl)-1H-[1,2,3]triazol-4-yl]-2-methoxy-phenyl}-methanone

Sources & evidence

ORD record
ord-846bf8fceb0e4dd28a5256e6114dec20
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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