Ammonia → HCID 20071066, compound

HRID 231375Notes

Reaction equation

HRID 231375 reaction equation
Cl[C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([NH:9][CH3:10])[C:3]=1[N+:11]([O-:13])=[O:12].[NH3:14]>O.C(O)C>[Cl:8][C:6]1[CH:5]=[C:4]([NH:9][CH3:10])[C:3]([N+:11]([O-:13])=[O:12])=[C:2]([NH2:14])[CH:7]=1

Participants

5

Reactant 2

HCID 222AmmoniaHCID 20071071HCID 20071071, compound

Product 1

HCID 20071066HCID 20071066, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

0.034 mole (7.5 g) of 2,4-dichloro-6-methylaminonitrobenzene is added to 100 ml of a 28% solution of ammonia in water and 50 ml of ethanol in an autoclave. The reaction medium is heated for 12 hours at 145°-150° C., the pressure being 12 kg/cm2. The product expected precipitates from the reaction medium on cooling. After draining and re-impasting in water, it is dried by heating under vacuum in the presence of phosphorous pentoxide. Recrystallized from isopropanol, it melts at 129° C.

Workup

  1. temperatureThe reaction medium is heated for 12 hours at 145°-150° C.
  2. customThe product expected precipitates from the reaction medium
  3. temperatureon cooling
  4. customit is dried
  5. temperatureby heating under vacuum in the presence of phosphorous pentoxide
  6. customRecrystallized from isopropanol, it melts at 129° C.

Sources & evidence

ORD record
ord-a4fe7d87c5e74771a36a028cfe2c8f13
Source dataset
uspto-grants-1989_07
Patent number
US04845293

Reaction notes

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