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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2313826Generated: November 1, 2026

Tetrahydrofuran → Methyl [4-(2-chlorophenyl)-2-(4-hydroxyphenyl)thien-3-yl]acetate

https://huagongshe.com/reaction/2313826

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant2-Chlorophenylboronic acidHCID 2734322—
Reactant4-(tert-Butyldimethylsilyloxy)phenylboronic Acid (contains varying amounts of Anhydride)HCID 11107815—
ReactantMethyl [4-bromo-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)thien-3-yl]acetateHCID 86607177—
ReactantMethyl [2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-(2-chlorophenyl)thien-3-yl]acetateHCID 86607178—
ProductMethyl [4-(2-chlorophenyl)-2-(4-hydroxyphenyl)thien-3-yl]acetateHCID 86607176—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-4f61eeb650134d3bb65e72999ee6065e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)