4-amino-2-methyl-2,3-dihydro-1H-isoindole-1,3-dione → Diethyl[3-methoxy-4-({4-[(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl)amino]-5-(trifluoromethyl)pyrimidin-2-yl}amino)benzyl]phosphonate
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:30][c:31]1[c:32]2[c:36]([cH:37][cH:38][cH:39]1)[C:35](=[O:40])[N:34]([CH3:41])[C:33]2=[O:42]>>[c:2]1([NH:30][c:31]2[c:32]3[c:36]([cH:37][cH:38][cH:39]2)[C:35](=[O:40])[N:34]([CH3:41])[C:33]3=[O:42])[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e34a483ad22045d396d0aa3c463ba43d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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