4-Methanesulfonyl-6-(piperazin-1-ylmethyl)-3,4-dihydro-2H-benzo[1,4]oxazine → 4-Methanesulfonyl-6-{4-[2-(2-methylquinazolin-5-yloxy)ethyl]piperazin-1-ylmethyl}-3,4-dihydro-2H-benzo[1,4]oxazine

HRID 2313975Notes

Reaction equation

HRID 2313975 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][O:8][c:9]2[c:10]1[cH:11][c:12]([CH2:15][N:16]1[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1)[cH:13][cH:14]2.[CH3:22][S:23]([O:24][CH2:27][CH2:28][O:29][c:30]1[c:31]2[cH:32][n:33][c:34]([CH3:40])[n:35][c:36]2[cH:37][cH:38][cH:39]1)(=[O:25])=[O:26]>>[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][CH2:7][O:8][c:9]2[c:10]1[cH:11][c:12]([CH2:15][N:16]1[CH2:17][CH2:18][N:19]([CH2:27][CH2:28][O:29][c:30]3[c:31]4[cH:32][n:33][c:34]([CH3:40])[n:35][c:36]4[cH:37][cH:38][cH:39]3)[CH2:20][CH2:21]1)[cH:13][cH:14]2

Participants

3

Reactant 2

HCID 112091394-Methanesulfonyl-6-(piperazin-1-ylmethyl)-3,4-dihydro-2H-benzo[1,4]oxazineHCID 179651395-(2-(Methanesulfonyloxy)ethoxy)-2-methylquinazoline

Product 1

HCID 101523024-Methanesulfonyl-6-{4-[2-(2-methylquinazolin-5-yloxy)ethyl]piperazin-1-ylmethyl}-3,4-dihydro-2H-benzo[1,4]oxazine

Sources & evidence

ORD record
ord-5fb61979637444bfbe0530035341b60e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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