Acetic Acid → 3,4-dihydro-6-(1,1-dimethylethyl)-8-iodo-1'-methylspiro[2H-1,3-benzoxazin-2,4'-piperidine]
Reaction equation
[CH3:15][N:16]1[CH2:17][CH2:18][C:19](=[O:22])[CH2:20][CH2:21]1.[CH3:23][C:24](=[O:25])[OH:26].[NH2:1][CH2:2][c:3]1[c:4]([OH:14])[c:5]([I:13])[cH:6][c:7]([C:9]([CH3:10])([CH3:11])[CH3:12])[cH:8]1.[cH:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[NH:1]1[CH2:2][c:3]2[c:4]([c:5]([I:13])[cH:6][c:7]([C:9]([CH3:10])([CH3:11])[CH3:12])[cH:8]2)[O:14][C:19]12[CH2:18][CH2:17][N:16]([CH3:15])[CH2:21][CH2:20]2Participants
5
Sources & evidence
- ORD record
- ord-951930dbe50b48a1bfb308905d092e03
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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