HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[(2-Chloro-4-fluoro-5-nitrophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone → (2-Chloro-4-fluoro-5-aminophenyl)methyl-4,4-dimethyl-3-isoxazolidinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[(2-Chloro-4-fluoro-5-nitrophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone | HCID 20032374 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (2-Chloro-4-fluoro-5-aminophenyl)methyl-4,4-dimethyl-3-isoxazolidinone | HCID 20032369 | — |
Reaction Steps
By the method of Example 3, Step C, 16.0 g (0.052 mole) of 2-[(2-chloro-4-fluoro-5-nitrophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone was hydrogenated in the presence of 0.2 g of platinum oxide in 250 ml of ethanol, yielding 2-[(2-chloro-4-fluoro-5-aminophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04846882 |
| Source dataset | uspto-grants-1989_07 |
| ORD ID | ord-0238027b9f574665b9e7188a581ccae6 |
| Source note | uspto-grants-1989_07 |