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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2314727Generated: November 2, 2026

Tetrahydrofuran → Racemic (2'S,3S,4'R)-6-chloro-4'-[5-chloro-2-(1-cyanocarbamoyl-1-methyl-ethoxy)-phenyl]-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dione

https://huagongshe.com/reaction/2314727

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantCyanamideHCID 9864—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant6-chloro-4'-[5-chloro-2-(1-hydroxycarbonyl-1-methyl-ethoxy)-phenyl]-2'-(5-fluoro-2-methyl-phenyl) spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 76568015—
ProductRacemic (2'S,3S,4'R)-6-chloro-4'-[5-chloro-2-(1-cyanocarbamoyl-1-methyl-ethoxy)-phenyl]-2'-(5-fluoro-2-methyl-phenyl)spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 74928460—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-b9f6a41204a5440a87008b70a1230f41
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)