Methanol → 2-(4-chloro-3-trifluoromethyl-benzyl)-4-oxo-4-[4-(2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-piperidin-1-yl]-butanoic acid
Reaction equation
[CH3:40][OH:41].[Cl:3][c:4]1[c:5]([C:36]([F:37])([F:38])[F:39])[cH:6][c:7]([CH2:8][CH:9]([C:10](=[O:11])[O:12][CH3:13])[CH2:14][C:15]([N:16]2[CH2:17][CH2:18][CH:19]([N:22]3[C:23](=[O:32])[NH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[CH2:31]3)[CH2:20][CH2:21]2)=[O:33])[cH:34][cH:35]1.[Na+:2].[OH-:1].[OH2:42]>>[Cl:3][c:4]1[c:5]([C:36]([F:37])([F:38])[F:39])[cH:6][c:7]([CH2:8][CH:9]([C:10](=[O:11])[OH:12])[CH2:14][C:15]([N:16]2[CH2:17][CH2:18][CH:19]([N:22]3[C:23](=[O:32])[NH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]4[CH2:31]3)[CH2:20][CH2:21]2)=[O:33])[cH:34][cH:35]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-faa2a190d8154efb81dd64f85ddc51c6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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