3-{2-(3-Chloro-5-fluorophenyl)-5-[(4-oxoimidazolidin-1-yl)carbonyl]thiophen-3-yl}benzenecarbonitrile → 1-{[4-(3-Chloro-4-fluorophenyl)-5-(3-chloro-5-fluorophenyl)thiophen-2-yl]carbonyl}imidazolidin-4-one
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:5]2[s:6][c:7]([C:8](=[O:9])[N:24]3[CH2:25][NH:26][C:27](=[O:29])[CH2:28]3)[cH:10][c:11]2-[c:12]2[cH:13][c:14]([C:15]#[N:16])[cH:17][cH:18][cH:19]2)[cH:20][c:21]([F:22])[cH:23]1.[Cl:30][c:31]1[cH:32][c:33](-[c:38]2[cH:39][c:40]([C:51](=[O:52])[OH:53])[s:41][c:42]2-[c:43]2[cH:44][c:45]([Cl:50])[cH:46][c:47]([F:49])[cH:48]2)[cH:34][cH:35][c:36]1[F:37]>>[N:24]1([C:51]([c:40]2[cH:39][c:38](-[c:33]3[cH:32][c:31]([Cl:30])[c:36]([F:37])[cH:35][cH:34]3)[c:42](-[c:43]3[cH:44][c:45]([Cl:50])[cH:46][c:47]([F:49])[cH:48]3)[s:41]2)=[O:53])[CH2:25][NH:26][C:27](=[O:29])[CH2:28]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-21109daa3e194498a74e71bb7103e7c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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