Acetate → 5-{1-[(2,5-difluorophenyl)acetyl]-2,3-dihydro-1H-indol-5-yl}thieno[2,3-d]pyrimidin-4-amine
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([C:11]([CH2:12][c:13]1[c:14]([F:20])[cH:15][cH:16][c:17]([F:19])[cH:18]1)=[O:21])[CH2:6][CH2:5]2.[Br:27][c:28]1[cH:29][s:30][c:31]2[n:32][cH:33][n:34][c:35]([NH2:37])[c:36]12.[CH2:48]1[O:49][CH2:50][CH2:51][O:52][CH2:53]1.[CH3:23][C:24](=[O:25])[O-:26].[CH3:43][CH2:44][O:45][CH2:46][CH3:47].[K+:22].[Na+:42].[O-:38][C:39]([OH:40])=[O:41]>>[c:2]1(-[c:28]2[cH:29][s:30][c:31]3[n:32][cH:33][n:34][c:35]([NH2:37])[c:36]23)[cH:3][c:4]2[c:8]([cH:9][cH:10]1)[N:7]([C:11]([CH2:12][c:13]1[c:14]([F:20])[cH:15][cH:16][c:17]([F:19])[cH:18]1)=[O:21])[CH2:6][CH2:5]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-ea4789d6b7b6455ea233fee0efe17535
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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