Ethylenediamine → N-(3,4-Difluorobenzyl)-2-(4,5-dihydro-1H-imidazol-2-yl)-6-isopropoxy-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamide
Reaction equation
[CH2:35]([CH2:36][NH2:37])[NH2:38].[Cl:47][CH2:48][Cl:49].[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[c:10]([CH:29]=[O:30])[n:11]([CH2:22][c:23]3[n:24][cH:25][cH:26][cH:27][cH:28]3)[c:12]3[cH:13][c:14]([O:18][CH:19]([CH3:20])[CH3:21])[cH:15][cH:16][c:17]23)[cH:31][cH:32][c:33]1[F:34].[O:39]=[C:40]1[N:41]([Br:42])[C:43](=[O:44])[CH2:45][CH2:46]1>>[F:1][c:2]1[cH:3][c:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[c:10]([C:29]3=[N:38][CH2:35][CH2:36][NH:37]3)[n:11]([CH2:22][c:23]3[n:24][cH:25][cH:26][cH:27][cH:28]3)[c:12]3[cH:13][c:14]([O:18][CH:19]([CH3:20])[CH3:21])[cH:15][cH:16][c:17]23)[cH:31][cH:32][c:33]1[F:34]Participants
5
Sources & evidence
- ORD record
- ord-a0d7318c44144eaf802b5f9e3ba7c916
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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