N1-(3-fluoro-4-(thieno[3,2-b]pyridin-7-yloxy)phenyl)-N3-phenylmalonamide → N'-[4-[2-[3-(dimethylamino)pyrrolidine-1-carbonyl]thieno[3,2-b]pyridin-7-yl]oxy-3-fluorophenyl]-N-phenylpropanediamide
Reaction equation
[F:1][c:2]1[cH:3][c:4]([NH:18][C:19]([CH2:20][C:21](=[O:22])[NH:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)=[O:30])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][cH:16][s:17]2.[F:31][c:32]1[cH:33][c:34]([NH2:35])[cH:36][cH:37][c:38]1[O:39][c:40]1[cH:41][cH:42][n:43][c:44]2[cH:45][c:46](-[c:47]3[n:48]([CH3:49])[cH:50][cH:51][n:52]3)[s:53][c:54]12.[NH2:55][c:56]1[cH:57][cH:58][c:59]([O:60][c:61]2[cH:62][cH:63][n:64][c:65]3[cH:66][c:67]([C:70](=[O:71])[N:72]4[CH2:73][CH:74]([N:77]([CH3:78])[CH3:79])[CH2:75][CH2:76]4)[s:68][c:69]23)[c:80]([F:81])[cH:82]1>>[F:1][c:2]1[cH:3][c:4]([NH:18][C:19]([CH2:20][C:21](=[O:22])[NH:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)=[O:30])[cH:5][cH:6][c:7]1[O:8][c:9]1[c:10]2[c:11]([n:12][cH:13][cH:14]1)[cH:15][c:16]([C:70](=[O:71])[N:72]1[CH2:73][CH:74]([N:77]([CH3:78])[CH3:79])[CH2:75][CH2:76]1)[s:17]2Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-98805be2510341f3ba15c8d0c0551680
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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