3-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole → 3-Fluoro-2-methyl-4-(trifluoromethyl)-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-5-carbonitrile

HRID 2315551Notes

Reaction equation

HRID 2315551 reaction equation
[Cl:18][CH2:19][c:20]1[n:21][o:22][c:23](-[c:25]2[cH:26][c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:29][cH:30]2)[n:24]1.[F:1][c:2]1[c:3]([CH3:17])[nH:4][c:5]2[cH:6][cH:7][c:8]([C:15]#[N:16])[c:9]([C:11]([F:12])([F:13])[F:14])[c:10]12>>[F:1][c:2]1[c:3]([CH3:17])[n:4]([CH2:19][c:20]2[n:21][o:22][c:23](-[c:25]3[cH:26][c:27]([C:31]([F:32])([F:33])[F:34])[cH:28][cH:29][cH:30]3)[n:24]2)[c:5]2[cH:6][cH:7][c:8]([C:15]#[N:16])[c:9]([C:11]([F:12])([F:13])[F:14])[c:10]12

Participants

3

Reactant 2

HCID 27366223-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazoleHCID 578003103-fluoro-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Product 1

HCID 578005213-Fluoro-2-methyl-4-(trifluoromethyl)-1-({5-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-1H-indole-5-carbonitrile

Sources & evidence

ORD record
ord-0760dacd0d1649bb910a0dc9cd96c07e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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