Acetic Acid → 1-(4-fluorophenylmethyl)-N-[1-[2-(2-pyrazinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine

HRID 2315826Notes

Reaction equation

HRID 2315826 reaction equation
[CH3:33][C:34](=[O:35])[OH:36].[CH3:37][OH:38].[CH:1](=[CH2:2])[c:3]1[n:4][cH:5][cH:6][n:7][cH:8]1.[F:9][c:10]1[cH:11][cH:12][c:13]([CH2:16][n:17]2[c:18]([NH:26][CH:27]3[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]3)[n:19][c:20]3[c:21]2[cH:22][cH:23][cH:24][cH:25]3)[cH:14][cH:15]1>>[CH2:1]([CH2:2][N:30]1[CH2:29][CH2:28][CH:27]([NH:26][c:18]2[n:17]([CH2:16][c:13]3[cH:12][cH:11][c:10]([F:9])[cH:15][cH:14]3)[c:21]3[c:20]([n:19]2)[cH:25][cH:24][cH:23][cH:22]3)[CH2:32][CH2:31]1)[c:3]1[n:4][cH:5][cH:6][n:7][cH:8]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 887MethanolHCID 77840VinylpyrazineHCID 123618Tecastemizole

Product 1

HCID 135881191-(4-fluorophenylmethyl)-N-[1-[2-(2-pyrazinyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine

Sources & evidence

ORD record
ord-b5ca3941aae643879ada60dc980d3be0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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