反应详情

A mixture of 3,5-bis(1,1-dimethylethyl)-4-hydroxyphenylthiocyanate (238 g, 0.90 mole), triethylphosphite (225 g, 1.35 mole), water (200 g), and methanol (2000 ml) was stirred at reflux for two hours. Upon cooling, the mixture was concentrated in vacuo. The residue was triturated with water, and the solid was collected by filtration and air dried. Recrystallization from aqueous methanol gave the title compound, m.p. 69°-71°.

1. temperatureat reflux for two hours
2. temperatureUpon cooling
3. concentrationthe mixture was concentrated in vacuo
4. customThe residue was triturated with water
5. filtrationthe solid was collected by filtration and air
6. customdried
7. customRecrystallization from aqueous methanol