Ammonium thiocyanate → HCID 20033901, compound

Participants

Reaction Steps

A mixture of 4,6-di-t-butylresorcinol (25.0 g, 112 mmole) and ammonium thiocyanate (18.0 g, 235 mmole) in methanol (100 ml) was stirred for 24 hours. The mixture was cooled to 0° and chlorine gas was bubbled through the solution for one hour. After the mixture was stirred for an additional hour at 0°, ammonia gas was bubbled through for one hour. A solid was removed by filtration and the filrate was concentrated in vacuo. Chromatography on silica gel and recrystallization from hexane gave the title compound.

Provenance & Evidence