3,3,3-Trifluoro-1-propanol → 5-(3,3,3-Trifluoro-propoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([I:17])[cH:14][c:15]2[CH2:16]1.[F:18][C:19]([CH2:20][CH2:21][OH:22])([F:23])[F:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([O:22][CH2:21][CH2:20][C:19]([F:18])([F:23])[F:24])[cH:14][c:15]2[CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-81c19cfc8d97432fa8f3d126398a889d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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