4-Methylquinuclidine-3-carbonyl chloride → N-[1-[2-(4-fluorophenyl)ethyl]pyrrolidin-3-yl]-4-methyl-1-azabicyclo[2.2.2]octane-3-carboxamide
Reaction equation
[CH3:1][C:2]12[CH:3]([C:10](=[O:11])[Cl:12])[CH2:4][N:5]([CH2:6][CH2:7]1)[CH2:8][CH2:9]2.[NH2:13][CH:14]1[CH2:15][N:16]([CH2:19][CH2:20][c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[CH2:17][CH2:18]1>>[CH3:1][C:2]12[CH:3]([C:10](=[O:11])[NH:13][CH:14]3[CH2:15][N:16]([CH2:19][CH2:20][c:21]4[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]4)[CH2:17][CH2:18]3)[CH2:4][N:5]([CH2:6][CH2:7]1)[CH2:8][CH2:9]2Participants
3
Sources & evidence
- ORD record
- ord-95be34cade894de9a26a09b105715180
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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