Acetyl chloride → 2n-Propyl-4-acetyl-6-t-butylphenol

HRID 231613Notes

Reaction equation

[CH2:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([C:10]([CH3:13])([CH3:12])[CH3:11])[C:5]=1[OH:14])[CH2:2][CH3:3].[C:15](Cl)(=[O:17])[CH3:16]>>[CH2:1]([C:4]1[CH:9]=[C:8]([C:15](=[O:17])[CH3:16])[CH:7]=[C:6]([C:10]([CH3:13])([CH3:12])[CH3:11])[C:5]=1[OH:14])[CH2:2][CH3:3]

Participants

Reactant 2

HCID 6367Acetyl chloride

HCID 146720432-n-Propyl-6-t-butylphenol

Product 1

HCID 146720492n-Propyl-4-acetyl-6-t-butylphenol

Procedure

Intermediate 2-n-propyl-6-t-butylphenol is reacted with acetyl chloride, using the conditions outlined in Example 3 above, to give 2n-propyl-4-acetyl-6-t-butylphenol. This compound is then converted to 2-n-propyl-4-(6'-heptynoyl)-6-t-butylphenol according to the following procedure:

Sources & evidence

ORD record: ord-8d99b091c44843f390ee20132ff47885
Source dataset: uspto-grants-1989_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04847303

Reaction notes

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