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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2316175Generated: November 1, 2026

Sodium ion → 8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-phenylmethoxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrile

https://huagongshe.com/reaction/2316175

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantBenzyl BromideHCID 7498—
ReactantTetrahydrofuranHCID 8028—
Reactant18-Crown-6HCID 28557—
ReactantHydrideHCID 166653—
Reactant8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-hydroxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrileHCID 88039642—
Product8-Benzyl-2-[1-[3,5-bis(trifluoromethyl)phenyl]-2-phenylmethoxyethoxy]-1-phenyl-8-azabicyclo[3.2.1]octane-6-carbonitrileHCID 88039036—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-5cf664559e2946c4a32a143c235f77a6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)