(5-Fluoropyridin-3-yl)methanamine → 4-methyl-N-((6-methylpyrazin-2-yl)methyl)-2-(2-oxo-3-(4,4,4-trifluorobutyl)imidazolidin-1-yl)thiazole-5-carboxamide
Reaction equation
[CH3:10][c:11]1[cH:12][n:13][cH:14][c:15]([CH2:17][NH2:18])[n:16]1.[CH3:19][c:20]1[n:21][c:22]([N:28]2[C:29](=[O:40])[N:30]([CH2:33][CH2:34][CH2:35][C:36]([F:37])([F:38])[F:39])[CH2:31][CH2:32]2)[s:23][c:24]1[C:25](=[O:26])[OH:27].[F:1][c:2]1[cH:3][c:4]([CH2:5][NH2:6])[cH:7][n:8][cH:9]1>>[CH3:10][c:11]1[cH:12][n:13][cH:14][c:15]([CH2:17][NH:18][C:25]([c:24]2[c:20]([CH3:19])[n:21][c:22]([N:28]3[C:29](=[O:40])[N:30]([CH2:33][CH2:34][CH2:35][C:36]([F:37])([F:38])[F:39])[CH2:31][CH2:32]3)[s:23]2)=[O:26])[n:16]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-d25b57fa3ebb4c3995fe2cc05772a689
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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