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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2316188Generated: November 1, 2026

Dichloromethane → (4-Amino-3-fluorophenyl)(4-(4-(2-(tert-butyldimethylsilyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl)benzyl)piperazin-1-yl)methanone

https://huagongshe.com/reaction/2316188

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactanttert-Butyldimethylsilyl chlorideHCID 28928—
Reactant1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
Reactant(4-Amino-3-fluorophenyl)(4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)benzyl)piperazin-1-yl)methanoneHCID 86638550—
Product(4-Amino-3-fluorophenyl)(4-(4-(2-(tert-butyldimethylsilyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl)benzyl)piperazin-1-yl)methanoneHCID 59175907—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-feeff90cd74745ee957b7f743f03a76f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)