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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2316289Generated: November 1, 2026

Hydrochloric Acid → 3-Cyano-5-[(1H-indazol-4-ylmethyl)-carbamoyl]-thiophene-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/2316289

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantTriethylamineHCID 8471—
ReactantHexafluorophosphateHCID 9886—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantO-benzotriazol-1-yl-tetramethyluroniumHCID 130500—
Reactant1-(1H-Indazol-4-yl)methanamineHCID 44119277—
Reactant3-Cyano-thiophene-2,5-dicarboxylic acid 2-methyl esterHCID 68227109—
Product3-Cyano-5-[(1H-indazol-4-ylmethyl)-carbamoyl]-thiophene-2-carboxylic acid methyl esterHCID 68226653—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (10/10)
ORD IDord-2d0271f563ca45b99981c7679a2d0631
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (10/10)