HCID 14229943, compound → HCID 14229944, compound

HRID 231632Notes

Reaction equation

HRID 231632 reaction equation
[C:1]([O:4][CH:5]([C:13]1[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][N:14]=1)[C:6]([NH:8][C:9]([CH3:12])([CH3:11])[CH3:10])=[O:7])(=[O:3])[CH3:2].[H][H]>O1CCOCC1.[Pd]>[C:9]([NH:8][C:6](=[O:7])[CH:5]([C:13]1[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][N:14]=1)[O:4][C:1](=[O:3])[CH3:2])([CH3:10])([CH3:11])[CH3:12]

Participants

5

Reactant 2

HCID 14229943HCID 14229943, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 14229944HCID 14229944, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumSolventHCID 312751,4-DioxaneSolvent

Procedure

5 g (16.9 mmol) of 2-acetoxy-2-(5-nitro-2-pyridyl)-N-tert.-butyl-acetamide are dissolved in 50 ml of 90% strength aqueous dioxane, 250 mg of 10% strength palladium-on-active charcoal are added and hydrogenation is carried out at room temperature until the uptake of hydrogen is complete. For working up, the catalyst is filtered off and the filtrate is evaporated. The residue is dried.

Workup

  1. additionare added
  2. filtrationthe catalyst is filtered off
  3. customthe filtrate is evaporated
  4. customThe residue is dried

Sources & evidence

ORD record
ord-dde91c47b7254469b672e7a380bea315
Source dataset
uspto-grants-1989_07
Patent number
US04847382

Reaction notes

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