5-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acid → (RS)-1-[5-(4-Fluoro-phenyl)-2-methyl-thiazol-4-yl]-1-(2-furo [3,2-b]-pyridin-2-ylmethyl-piperidin-1-yl)methanone

HRID 2316608Notes

Reaction equation

HRID 2316608 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:14](=[O:15])[OH:16])[n:10][c:11]([CH3:13])[s:12]2)[cH:6][cH:7]1.[NH:17]1[CH:18]([CH2:23][c:24]2[cH:25][c:26]3[n:27][cH:28][cH:29][cH:30][c:31]3[o:32]2)[CH2:19][CH2:20][CH2:21][CH2:22]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([C:14](=[O:16])[N:17]3[CH:18]([CH2:23][c:24]4[cH:25][c:26]5[n:27][cH:28][cH:29][cH:30][c:31]5[o:32]4)[CH2:19][CH2:20][CH2:21][CH2:22]3)[n:10][c:11]([CH3:13])[s:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 223241255-(4-Fluorophenyl)-2-methyl-1,3-thiazole-4-carboxylic acidHCID 23146382HCID 23146382, compound

Product 1

HCID 23146339(RS)-1-[5-(4-Fluoro-phenyl)-2-methyl-thiazol-4-yl]-1-(2-furo [3,2-b]-pyridin-2-ylmethyl-piperidin-1-yl)methanone

Sources & evidence

ORD record
ord-545aad9bcec9482c98024e30a12da20f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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